A case of nodular regenerative hyperplasia in a patient who had been taking didanosine

A case of nodular regenerative hyperplasia in a patient who had been taking didanosine

Purpose of study It is widely recognised that liver disease causes significant morbidity and mortality in HIV positive patients. Many patients are co-infected with hepatitis B and C, have increased alcohol intake or are on hepatotoxic medication e.g. nevirapine, which can cause acute hepatitis or liver cirrhosis. Nodular regenerative hyperplasia (NRH) is characterised by the presence of diffuse...

Nodular regenerative hyperplasia

Nodular Regenerative Hyperplasia

Introduction: Nodular regenerative hyperplasia (NRH) is a known etiology of noncirrhotic portal hypertension. Cases of biopsy-proven NRH in human immunodeficiency virus (HIV)–positive patients have been described. While these patients often have normal synthetic liver function, several reports described disease progression to liver failure. Case: We here present a 26-year-old woman with history...

Pulmonary Nodular Lymphoid Hyperplasia: A Rare Case Mimicking Malignancy

Pulmonary nodular lymphoid hyperplasia (PNLH) is a reactive lymphoid proliferation manifesting as multiple solitary nodules or localized infiltrates in the lungs. It is a type of benign lymphoproliferative disease that can affect the lungs. We present the case of a 41-year-old female patient with respiratory symptoms such as productive cough, left chest pain, and dyspnea. Imaging findings revea...

Nodular regenerative hyperplasia of the liver associated with didanosine persists for years even after its interruption.

The authors describe an HIV-positive patient with nodular regenerative hyperplasia of the liver with non-cirrhotic portal hypertension. Despite stopping the culprit drug, didanosine, the radiologic changes persisted for years. When evaluating liver pathologies, antiretroviral drugs must be included in the differential diagnosis, even when they have been stopped years ago.